It is the art of interlocking beads together with thread is both ancient and universal.  Madelyn's designs are a mixture of many different cultures and times. The technique is peyote stitch named by the Native Americans in the US. 
A very strong multifilament nylon thread is used.  The square glass beads are a high quality glass manufactured in Japan using novel techniques.  Many of the beads are plated with precious metals such as 24K gold, rhodium and palladium. 
Also used, are lot of silver-lined colored beads to create a lot of sparkle, making the finished piece look like
small dots of colored light  woven together.

There are very few artists that work with beads this small ( about 300 per square inch), or create pieces with such intricate patterns and colors.